Okay, I too have been having this problem since 1.0 launch. I've played KSP since .18 and used opengl since .23.5. I may have narrowed this down to what I believe is an issue when the game is launched in windowed mode. First, my setup is an HDMI monitor running 1920x1080 as monitor 1. Second monitor is running DVI on 1680x1050. I use Nvidia 770GTX ver 340.52 drivers. Second monitor is running a basic Nvidia 9500 card. I believe this issue stems from the game opening itself right in the middle of the two monitors therefore causing it to try and adjust to the lowest resolution monitor. Simple test I ran, was to remove the '-popupwindow' launch option and disable the 'fake full-screen' option from the launcher. Once these options were changed, I was able to run the game in 'windowed' (not borderless) and also in full-screen. However the windowed version started in-between the two monitors. Hopefully this will help anyone else in the future. There really isn't a fix that I know if besides starting in full-screen and then changing to windowed (Alt+Enter), until they fix this opening in-between two desktops issue. Edit: Apparently windowed mode with '-popupwindow -force-opengl' inherently carries this issue, as Alt+Enter just causes the same crash for me.