This comment prompted me to revisit my designs for a Mk2 Moho Lander and do a full test flight. The (mediocre) results can be found below.
Do you have a nifty Mk2 payload? Please reply below!
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Skyfly XI + MoEM IX (Steam Workshop)
The test flight of Skyfly XI + Moho Excursion Module VIII completed its objective to land on Moho, refuel with ISRU, and return to Moho orbit with enough fuel to land again.
So the trip and biome hopping is doable, but landing and mining is a pai