I am having what sounds like the same issue. On the launch of my first station, my persistent save becomes corrupted. If I manage to get back to KSC, I can enter the contracts or astronaut buildings, but cannot then to the KSC scene. I'm using all of the mods you are, Perry, and then some, so I downloaded your save game hoping that there was a bugged part that we had in common. No such luck; all of the parts that we are both using are stock or MechJeb. I did, however, have the following successes: 1) By pressing escape from the KSC scene, I managed to load your quicksave file. It is safe and uncorrupted. I've noticed in my own game that the first sign of corruption is that I cannot quicksave, but I recommend backing this up anyway before proceeding. 2) Having loaded the quicksave, I launched the Ike Station 1 craft and achieved a stable orbit. From there, I was able to return to KSC and enter buildings. I do not believe this ship is a problem. To anyone else having this problem, I recommend loading your quicksave as I mentioned above, then rebuilding your craft.