We have a few pretty big projects at work, and to go from u4.6 to u5rc3 was pretty easy. TrippleA prototype with very complicated physics went smoothly, just had to fix the code because they removed properties on MonoBehaviour, so now you have to go getComponent instead... simple small tweaks really... Another mobile game project - exactly the same changes required to get it running, but here we will be changing the whole animation, ui and audio systems to use the new u5 stuff...