I've been playing KSP on my iMac for a while now, suffering through the crashes. Last night, I found a post on reddit that describes how to update the Unity engine to 64bit inside the KSP package. I did this. It's amazing.
Since, I've installed some serious visual mods and run at over 5GB, no crashes, period.
Another thing: if you have a retina mac, switch to a non-retina resolution before opening. Specifically, a non-HDPI resolution.
https://www.reddit.com/r/KerbalSpaceProgram/comments/3laqnf/psa_ksp_64_bit_works_on_mac_os_x/