After flying around with rapiers and all sorts of things i decided to try to do without them. Even without ramjets and the coned intakes. Here it is , panthers and and nukes only, no oxidizer at all, using parts that are available rather low in the tech tree.
Ascent profile for this is somewhat unusual darting upwards sharply with panthers in wet mode until you get up to about 700-800m/s speed (panthers in wet mode since takeoff), then around 8k panthers are getting too fast and too high, starting to lose the power - time to switch on the nukes. Yes they only have ~50kN at these altitudes but it doesn't matter, aim for a ~30-40 degree ascent, keep watching your periapsis, as you keep this crazy ascent it will go further in time eventually coming to about 75km and 1m30s away from you, aim for prograde do the maneuver nodes etc. On my quite bad takeoff here i got to orbit with 628 liq. fuel left, i think not the worst i have done. On descent it's easy to lose control - to recover pump the fuel forwards, invoke panthers if necessary to regain control. Lands quite easily to ground at the end.
Some more notes - i have bound "Lights" to close the intakes, i do it around 24-25k when the panthers lose the last of their thrust. When in orbit i switch the panthers to dry mode (fuel efficiency for landing maneuvers). After retrograde burn for deorbit i disable the nukes already in space and enable the panthers (and open the air intakes again!). As seen on the screenshot i actually had almost 25% fuel left after deorbit and landing, after some pretty bad flying. So you can fool around in orbit as well if you wish (those nukes are crazy efficient). The part after command module is structural fuselage, just to make the plane a bit longer and more natural. Into the service bay i hid some batteries, 1x6 solar panels and a probodyne hecs (so i could use non-pilots to fly).
Hope this helps people who don't have rapiers yet in career, but really badly want just a space plane