if you are in the same style that i am, i will say forget everything else other than science points and pay all your effort on two things:
1. spaceplane parts and nuclear engine
2. station parts and surface base
the reason behind it is once you unlock spaceplane and nuclear, you can go anywhere you want for free, or nearly free if you can't land your SSTO right on the runway, you could transfer tourist for money by SSTO and also deliver satellites with cargo SSTO, just imagine it that you pay nothing to transfer anything into space! you could evencut off the funds for propellant if you set a refueling station just beside the runway, launch with empty fuel tank and refuel after landing, think about it, you may get money from the launch because you go with empty and back with full of fuel : the only resource you used is ore, which is free.
and there need not that much explain on why you need to have station parts, it's pretty obvious that you can get lots of science point from a small amount of data, and it's not a dream to unlock everything by a LKO station.
BTW, station is still useful after you unlock every single parts, the science point could convert into funds by using one of the strategy and it's really large amount of money...