I think that, if I could find any small piece of criticism of KSP that I would like addressed in KSP2, is that the campaign should have a win condition.
Currently the win condition is, afaik, just unlocking the tech tree. But that means that instead of unlocking parts and tech as a means to do more complex missions, it's the goal itself. I absolutely love the campaign and the way it is set up, so I think it would be nice if there could be a some small box to tick to say "hey, you beat the campaign". For me, I'd like to be unlocking late-game techs as a means to beat the campaign. A win condition shouldn't be too hard to find, you don't even have to pursue the condition if you just enjoy the campaign as it is. Perhaps something like "hey, plant a flag on all of these bodies" or "reach a reputation of 99%" or something. beats me.
It's not overly necessary. I'm enjoying KSP so much even without an actual goal to pursue in the campaign. But I really like trying to design ships that do something without having access to every part. Like I built an SSTO out of turbojets and rockets. It's payload capacity is probably about 100 kg but I had so much fun trying to accomplish that without Rapiers or Nukes.