Thanks a lot. I've found the issue! It seems KER is very sensible of the way you install it (maybe the way it uses serialization):
Before I've used Vortex to manage my mods, wich uses symlinks and hardlinks to move the mod files in the GameData folder.
I have removed all the loose files in KSP directory, checked file integrity with steam and manually placed only KER in GameData folder and it worked (60fps).
Then I've set Vortex to copy files instead of making links and it didn't work.
In the final solution I have installed all the other mods with Vortex links, but disabled KER into Vortex and placed it manually. This method works for all combinations of KER/KSP.