My first few flights in KSP 2 have been broadly positive. Not without the occasional glitch, but mostly usable:
Got a simple 2 stage probe into orbit around Kerbin and back again
Took 3 Kerbals to Minmus, planted a flag, and returned almost* safely
Briefly tried to drive a rover around the runway
*The Minmus return vessel had a 3-kerbal pod, which apparently doesn't slow much below 50m/s with the single parachute I had fitted. Oops!
Positives I've seen compared to good old vanilla KSP1:
Graphically flying over terrain is amazing, far more like a planet and less like a blocky ball. Kerbin and Minmus both have had incredible surface, terrain, biome and lighting updates. Also clouds
A lot of the basic mechanics worked roughly as hoped - staging, launching, SAS for directions, accel/decel to change orbits, etc so for me at least the game was playable
Putting spaceships into orbit and landing them places is still fun
Map SOI enter/leave graphics are a nice touch
Some of the glitches, oddities and Early-Access behaviours I've seen:
Structural booster fixings/decouplers not playing nicely after launch leading to explosions - not sure whether this is game behaviour or if I just need to rethink some "standard" designs I've used for KSP1 in the new game
Odd EVA jetpack behaviour where after turning on & off jetpacks on EVA and switching between a few kerbals their packs wouldn't reignite - thankfully jumping on Minmus works
Had a couple of debris parts in the Tracking centre that I seem unable to delete
Orbits after a change in SOI don't appear to always predict correctly - while returning from Minmus the path prediction suggested I was going to leave Kerbin's SOI until I had left Minmus' SOI
I haven't found the thrust-to-weight ratio indicators for VAB design of stages yet and I miss them!
The game is definitely Early Access, but also has a lot of the positives about it that made KSP one such a success.
~Vin