my solution is that: You are sending 280 tons of fuel to LKO with my rocket forum.kerbalspaceprogram.com/showthread.php/32110-super-heavy-refule-ship-280-tons-to-orbit You are building some craft similar to eve starting stage from this video
but without nuclear engine , with remount control and 3 kerbal seats . Put it on top of some big rocket and mach all Aerospikes to one action group, add some rcs tank and docking ports at top of rocket. Then fly it with big rocket to about 30km activate Aerospikes and get it to orbit . Send small space station with some nuclear engines and dock it with return craft and big fuel ship in orbit . refuel return craft and fly to eve. When you arrive get on orbit and drop return craft to surface. you can separate rsc tanks and docking port. Take your kerbals back to orbit , get near to space station , then take them aboard the space station. Fly it to kerbin .