I too am having issues running Kethane 0.7.4 with KSP 0.21. I have installed MechJeb 2.0.8 (tweaked via another forum user to run), KAS for 0.20.1, and ISA MapSat X4r1. When I enter map view I can see the Kethane Scan Map window, but enabling it does not toggle the display. Zooming in and out of the body will cause it to flicker briefly, then disappear. Can't say if this happens on all bodies as I'm still tinkering on the Mun. I know I'm not alone in valuing the extra dimensions of game play your wonderful mod has created. Thank you for helping make KSP the game we love.