Okay. I performed the reset of fonts via method one and started KSP, still no juice on the buttons. I hadn't considered the fonts being an issue, even though that is what is missing from the buttons, but it still had no affect. So, I proceeded to perform the second method with SFC. This yielded some corrupt files that could not be fixed. After throwing the log into a text document it had to do with some .json files. So I warped over to google to see if there was a way to replace/fix these. That is when I stumbled upon this posting about a windows update installed on the 15th of May (I Last played shortly after 1.0.2 released on May 1st). Fix for KB3022345, I followed removing of this update and rescanned with SFC, no corrupt files found. So I reboot and start KSP again. Still no juice. After that went through I went into CCC to check for software updates for it, It showed an update was available for the drivers where the AMD Gaming Evolved software claims they are up to date. So I applied the available update. Reboot then KSP launch. Again, no juice. I am now going to attempt to install a fresh OS on a spare drive to see if that resolves the issue or not. I will be back in touch. Any other ideas or help will still be appreciated.