Help me verify the effect of the ingredient in this weight loss pill

[RainDreamer]

So, about the actual way the pill claim to reduce weight, I have been trying to translate a promotional material piece into English, and can be summarized as such (please excuse me if the translation is not very specific, I am not familiar with biochemistry lingo nor vietnamese):

Alpha-mangostin and 7-hydroxyfrullanolide has been proven by scientists to halt the formation and development of white fat cells through 2 ways:

Prevention of white fat cells accumulation, through inhibition of the nuclear receptor PPARγ(PPAR-gamma) right at the cell differentiation process to prevent new white fat cells from developing, thus decreasing white fat cells accumulation. This process happened in a molecular level.

Promoting white fat cells break down, by reducing the presence of Perilipin, the protein that protects the fat, helping lipase enzymes to approach the fat in the cells, liberate it from the cells and break it down, thus helping reducing white fat cells at fat accumulation area like the stomach, tights, and waist.

Further more, these 2 active ingredients also cause lipid to be more sensitive to lipolysis - inducing enzymes and increasing the concentration of adiponectin thus promoting a beneficial fat breakdown process that is the oxidation of fat inside the liver.

That is a lot of stuff to give to a lay person, enough to just make them go ahead and believe whatever they say. So, do you guys see any red flag in that, aside from the obvious one like no citation? I can do another translation pass if something seems off and require more careful translation.

[KSK]

So, about the actual way the pill claim to reduce weight, I have been trying to translate a promotional material piece into English, and can be summarized as such (please excuse me if the translation is not very specific, I am not familiar with biochemistry lingo nor vietnamese): That is a lot of stuff to give to a lay person, enough to just make them go ahead and believe whatever they say. So, do you guys see any red flag in that, aside from the obvious one like no citation? I can do another translation pass if something seems off and require more careful translation.

Pretty much what I said before. It sounds obvious but fat cells are there - well to store fat. Stopping fat cells from forming won't stop your body from making fat. At least I don't think it will. So where does all that fat go? Likewise enhancing lipolysis. A typical fat is a triglyceride, that is a molecule made of three long chain fatty acids joined to a molecule of glycerol. Lipolysis breaks that fat molecule back down to glycerol and fatty acids, both of which can then be further metabolised. But unless you're using enough energy to use up those fatty acids and glycerol... again where do they go?

I guess these pills might (heavy emphasis on the might) make it easier for your body to 'burn' fat as a source of energy. However using fat for energy is pretty much a measure of last resort - your body will metabolise almost anything else before it gives up and starts metabolising fat. So the same weight loss rules apply - eat less and exercise more. If you're not doing either of those, all I'm seeing that those pills will do is dump of a load of partially metabolised fat into your system. And that way lies all sorts of fun cardiovascular problems.

Caveat - the above is just extrapolation from what I know. It might well be wrong and I'll happily stand corrected by any of the proper biologists on this forum. However I still wouldn't touch those pills with a ten foot pole.

[0111narwhalz]

As I have littleto no relevant biochemical knowledge, I can offer only this: A different way to lose weight (or, often simply change fat into muscle): hiking. Go out into your local national forest and walk the trails for a few miles. Bring a friend, or an energetic dog. Eat a big, juicy cheeseburger after. It'll probably complement the yoga.

Oyes, and don't touch the "supplement." Half of those things need a "Do Not Ingest" sign.