Can both Career Mode and Sandbox Mode be balanced simultaneously?

[Red Iron Crown]

I think it just depends on what you, individually, think of as "balanced." There are far too many different ways to look at balance for there to only be one answer to this.

That's true. I started this thread more to gauge whether other players believed it was possible or not for both to be balanced, by their own standards, and their reasons for thinking so. What is your opinion, and why?