I had a nice largish exploration vessel (KSV-01 Duna was its name, really should have been KSV-02 but my first major vessel didn't get out of the atmosphere) in Kerbin orbit still with it LF booster rockets attached to the sides. I had originally equipped it with four smaller rockets outboard to help with boosting and four nuke rockets for the long burns for my first shot for Duna this play through but an error lead me with only one engine being attached. OK, I can work with this, no problem... I had the boosters partially fuelled from an orbital tanker, attached a too large lander to the front (meant for multiple uses around Duna), settled the seven crew into positions, got the thing oriented and started my burn... The first problem was the lander, the swaying got too much and it decided to not go on the trip to Duna less than a minute into the burn... OK I can work with this, I still got the vessel, it has the crew and science experiments, no need to worry. The boosters run out and I decouple them. Their little SRBs start their little burn to shoot them away from the vessel, only to fly straight into the four nuke rockets burning away. Now Jeb, Bill (or was it Bob?), and five others are in an elliptical orbit around Kerbin that takes them almost out to Minmus before screaming back in for a relatively close 125km flyby of Kerbin. Well crap... I look at the craft, look at the orbit, look at the craft... wait it still has that one lone rocket engine on it! And the fuel as well! I can use that to do something about this! So I turn on that lonely little engine, the entire ship starts spinning. I ease back on the throttle till it stops that spinning. RCS is firing, keeping the nose pointing in relatively the right direction, then that runs out. That's it, I'm done with that. Time to design a rescue boat. That only set them heading out halfway to Minmus, where they still orbit for now, enough food, water and O2 to last for nearly three years, a nuclear reactor to keep them in power. Meanwhile the new and improved KSV-03 Eve is on its merry way with three green crew on their first mission, likely to be stranded there until I can get a kethane miner out there to help them out. Turns out putting a L torus ring containing fuel right below the upper stabilizing rockets isn't that good of an idea, no real big loss there. Note: KSV-02 was the tanker I had used. Also seeing this thread made me decide to post that little adventure.
