PB666

Thats kind of what KRISPR does, except you just KRISPR the KRISPR genes. It does not go every where it can only move serially through the population. There are many variations. BTW we have been similR things since sthe seventies. One of my FFA projects was parasitized by screw worms, which was supposed irradicated in the US. The next week txA&M ag ext service had air drop boxes of sterile bluebottle flies to irradicate the females. This was 1979. There are all kinds of schemes. You could have schemes in which you could create a mosquito born parasite that eats falciparum.

http://www.space.com/33061-universe-expanding-faster-than-thought-hubble.html

Granted, you discover coywolf poo on your shoe after walking in a snowy forest. I wish I had a house on a beach with only pretty girls on it.

Banned for forgeting the period.

To be cut in a crowded elevator. Why do we use ancient greek in Modern English?

Imagine a very long space mission. We have to carry embryos of course, but the mission is so long that humans would not be able to repeat, and at the site we can only create so many people. By the time the generational voyage is over, the chromsomes have undergone fixation, you emplant embryos but this is not enough, you have at the end the genetic diversity of about 100 individuals. But the target is around 10,000. So that as your population grows you want to get this information back. Guess what, you don't need to send people, the genetic information is light speed distance to earth away, just send the information from 10,000 diverse individuals and maybe the 3 or 4th child an individual has add some genetic diversity so over time you can, with out sending a molecule, reconstitute the entire useful amount of human genetic diversity. Let recombination do the rest. Here's an example, you get to the planet, and you find, unbeknownst to you that a deadly virus is very popular in the environment and humans have no natural defenses to that virus, they cannot spread the disease but neither can they defend themselves (sort of like microbial neurotoxins). A molecular analysis of that virus reveals it has some similarities to a bacterial virus that infects bacteria of a certain species of Marsupials. But the marsupials are uneffected. So you examine their MHC class I antigens and you find that they have one molecule and a TLR receptor that provide the defense. Structural modeling reveals that altering the structure of these homologs in humans of two of these allows the production of an innate immune response. Synthesi of a small amount of viral antigen cause the immune system to produce alot of antibody, providing an immediate humoral defense to the environmental toxin. Problem solved. Another example, the environment has a high level of a certain heavy metal that causes premature aging and senility. That metal is pervasive as a consequence of a deep space asteroid collision with a moon of the planet that continues drop sufficient amounts to produce a health hazard. Remedial measure are quite expensive. A study of benthic worms on earth finds that certain worms living around volcanic outcrops have developed a resistance to this metal by producing a variant of Cytochrome P450 that specifically binds this metal and causes the metal to be excreted. You add a liver, bile duct targeting signal and it is excreted in the waste. It does not remove the toxin from the body, there is but the rate of turnover is faster and does less damage. The sequence of the P450 of human that can be modified can be sent, and engineered into embryos of individuals who are likely to end up exposed. Eventually the gene perculates through the population. Remember the saying god does not place dice with the universe. The same can be said about DNA, your chromosome is yours to play with, for good or for bad, but those who chose to play will be at selective advantages in most cases. Its not like inserting crystaline proteins from b. thurinigenis in to maize, this technology only tweeks what you have to make it do something ever so slightly different. I

Your talking about CRISPR, its been out there for about 2 years, longer than that. https://en.wikipedia.org/wiki/CRISPR Notice you haven't seen me panicking about it. Actually they are using it to edit antibody genes so that they can fight cancer and autoimmune disease, so . . . . . But even so, this just makes it a bit easier than before, we edit genes all the time, you put His tags or antibody tags, move them from human, to bacteria, to chinese hamsters overy cells, back to human cells again if you like. The point about CRISPR is that it offers the opportunity to remove some really bad diseases from human society while still at the embryonic stage. For example suppose you knew you carried a really bad gene, but you didn't know until after the child was say in its 20s. Well to bad for him/her. Something like Huntington's disease. Now you could do genetic testing in the womb, but then the parents have to make that dreaded A decision, and be you pro-life or pro-choice, if you are the parent and you have to make that decision, there is nothing pro about it. So now you can test embryos' but aren't you playing god with your genes, cause you are selecting out eggs just because of one defect on one chromosome. So a minimalist approach is just to fix that really, really bad guy and don't fix anything else. Here's another situation. You are a 55 year old male who spent most of his time studying science and deferring having children as you pushed forth your great new sciency stuff to change the world. But now you have decided to have children. But hold on a minute, while women are more at risk for chromosomal abnormalities after their 40s, mens proto-sperm cells are cooking with fire since the age of puberty, and by the time you are 55, those sperm are well done. So the child's risk for autism and schizophrenia go way up past the age for 40s for males. One thing we can do now at the 8 cell stage is do genome sequencing of both parents and match runs of identity. Then we can look for defects, most are harmless but some are nothing but bad news, so that these can be corrected at the 8 cell stage and then one cell can be used to develop a whole new being without the one or 2 defects. Win, win. Here's a third thing that can be done. In your body are plueripotent stem cells, they evolve into your immune system and blood cells. There are occasionally defects in these cells that affect the entire body, even though it only takes a few cells in the body to produce these. What we can do for affected individuals is to take the plueripotent stem cells from bone marrow and and fix the defective gene, often a premature stop codon, after expanding those cells in the lab we can put them back, walla, individual is not normal, but they can survive. Imagine giving the bubble boy (remember the boy trapped in a bubble at TCH in Texas medical center back in the 70s, John Travolta made a movie about him), a chance to leave the bubble. A forth thing that we can do. Suppose that you have been diagnosed with a lymphoma, and they have to irradiate all your immune cells to kill the cancer and give you a bone marrow graft from an unrelated individual, they have an HLA type that is close but not identical. With CRISPR we can sometimes make the HLA major antigen genes identicle. This means that we can stop the possibility of rejection. We can also remove some of your bone marrow cells, and fix the defect that causes the cancer, and put them back. In addition we can use CRISPR to specifically redesign a few of your natural killer cells to go after the lymphoma when a particular antibody, that we add, is present. In this way the Killer cells will identify one part of the antibody and the other part of the antibody will recognize the lymphoma and only the lymphoma. Does this sound wild, but such bivalent antibodies already exist and are being used. All we have to do is to alter the CD8+ cells so that they recognize the other part. Most cancers will be a thing of the past in 10 years. Radiation and these harsh therapies are not going to be the first line therapy. You are already seeing major increases in the life expectancy of melanoma and lung cancer patients. CRISPR is that which makes a hard job easier, it does not do something we could not do before, So now its possible to treat a patient who has months to live before they die instead of after they die, which is kind of useless. 'Hey sir, I manage to insert the right gene into your defective cells, Sir, Sir? Sir? Oh, no.'

Didn't leave, moved to Texas, is camped out, just about over the whole damn state. Here little el Nino, would you like to go back to California. They have nicer beaches. Santa Ana winds are nice this time of year.

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Dangerous in what way? beware, go back tomthe stone age, pay no attention to those large big gun woelding planet destroyer heading your way Or from lore, 'pay no attention to the bypass plans kept in that office on pluto' Would anyone like to borrow my el Nino for a bit, we all need to friggen dry out a wee little bit. Local river 10 feet over flood stage and its raining 4 inches per hour outside.

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You have to give me an accession number, otherwise i cannot answer you.

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alpha, commonly known as A. Enemy of infants, friend of the vain. Enemy of romans, friend of wallstreet. Answer to the question hon' why are you cooked. I should point out that its the most dangerous non-living entity, explaining its ghostly appearance.

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Its is an illustration of the most dangerous entity in the known universe. If you know what it is the you might also know why the pot of petunias said 'oh, not again'. Thats a view of his good side, to view all of his sides you need CN3D

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Was there any aliens in our galaxy four billin years ago, remember that we travel through space time. If youvwere asking whether if i had 2 dozen telescopes and the confirmed an Earth sun combo would i be interested in investigating it. I would have every telescope and deep space craft mission directed at trying to figure out if it would be a good target. That has nothing to do with my spaceships making it here. The questions regarded quantum teleportstion and entanglement were put forth 80 to 90 years ago, they've only started to be answered now,mand there are many caveots of QFT and QCD that have not been explored.. Dependending on how hard the technical feat is, it might take more effort than its worth or a considerably long time to answer. I mean if i wanted to cheaply seed sol system with life i would embed the late bombardment asteroids with survivable packages and let them do the dirty work of working out what should, would, could survive. The critical threshold is that if i am powerful enough to move my body from here to Nova Sol A and still be alive when i got there, tell you what, i don't need Earth. You would find me in the asteroid belt with robots redirecting comets from the kuiper belt to the outer asteroid belt where i intercept and stabilize them. I might have moved through Sol taken the objects i wanted, goten all the water i needed from comets, and because your ancestors were still clubbing lions with hand-axes, or worse, you never knew i past by, of course i passed by, everyone knows Earth is fated to be destroyed by a vogon constructor fleet inorder to build a hyperspace bypass.

2 (-) The dark side, its pulling you, you can feel its gravity getting heavier.

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Granted, you will only see news that has been confirmed accurate after a decade of research. I wish El nino were finished like for real, not in theory.

You mean like they settled on out ancient earth and became Archean, that the settled on our ancient earth and were eaten by Archean, that they attempted to terriform earth and failed at the very first biological step and Earth preceded on its evolution as if life occurred by neobiogenesis, or that they intentionally sent a spore ship with one archeaon prototype on board? As I will repeat, science gives no clue as to what cause biogenesis on Earth, but since that event occurred life has evolved on Earth by physical laws intrinsic to our solar system, there does not appear to be an outside hand involved in evolution. BTW, a species on its way to extinction realizing that its hopeless to try to go to the stars with such infrastructure might decide to send out seed ships in the direction of planets with archeotypical bacteria, constructed in a lab, that can survive under a wide variety of conditions and evolve. Therefore circumventing the problem of carrying themselves across space and hoping some other evolved species can figure out what to do. Another example if the last of the species was about to be destroyed by robots, they decide to do this in self preservation of some genetic material. The may have sent out seed ships to terriform, but they themselves never survived long enough to reach the colony, or something might have happened on Earth that delayed terriforming, such as the great bombardment, thinking that it was over they might have concluded earth was sterile and ignored it, as that star passed to a distant part of the milky way. Less likely maybe's. Maybe they also saw the great asteroid that wiped out the dinosaurs as a risk, maybe they see a future asteroid coming toward us, and have decided to wait until after all the dust has settled. Maybe a space fairing culture sees colonization as a hassle and prefers to inhabit systems with small bolloids around long lived red stars. Since these are often not easily visible they are great places to keep track of what local yellow star systems are doing, like us.

You said [the number representing t8r33] in your post, which was allowed since previous was in error, we default to the last good one.