I'm pretty sure the latest update (6.1) broke my save game. I couldn't click on the tracking station, and if I went into any of the buildings I could click on (contracts, crew hiring) it would break the menus and the only way to exit was hitting the windows key. At first I thought it was the crew roster mismatch error since it has the same symptoms but didn't have any issues there. Went through latest mods I installed since I last played, and I rolled back to the previous version and now everything works.