I have the same issues with OOM after a few times switching to VAB or SPH on a win10 16G RAM PC.
I play Realism overhaul with 70mods installed
My playable solution:
- Clean Install
- install the mods u (really) need via ckan, i focused on functionality not pimping graphics and so on
- install (via ckan) mem monitor or sth like that to watch your mem usage during game
-give active texture management (ckan) a try
-start Ksp.exe with -force-opengl -popupwindow
So, when i start the game my mem usage is at approx 2,7G
Every now and then it increases (VAB, Planet switching...)
When i reach the 3,4G... i restart the game for security reasons...
And yes i am serious, i did not found any other solution until now (without changing my OS).
I tried a lot and played several hundreds of hours... trying to colonize Mars ;-)
- I wish there could be sth. like mem cleaner to empty the unused/misfunctioning mem cache
P.S. The Graphic settings in Game (resolution, shader and so on) did not have any significant impact on mem usage, only on FPS...