I've found that I now try to squeeze as much as possible out of my missions. Previously I'd built a ship for one purpose, carry out it's mission, and send it home. However, now I try to see what else I can do to get more science. For example, I sent a small rocket (covered in science equipment) into low Kerbin orbit, intending for it to just orbit a few times and gather some data. However, having been in LKO several time, my science levels were depressingly low... so I went for a Mun flyby and then landed on Minmus (I reeeaally overestimate the amount of fuel I'm going to need!).