You start out with a kerbal and (maybe) a telescope. And science begins... Start out with small toy solid fuel rockets (that later become decoupler rockets?) and a very basic probe, add parachutes for increased hang time. That earn you more science points and maybe even something like fame that nets you grants or donations from the public/government, allowing for better telescopes and rockets. You can only see as far as your tools allow, so, for example, you may not know what the gravity is on mun. So you will have to decide whether to chance a trip there when you get upgraded enough or spend the money to launch a probe. Mission failures may or may not cost you fame depending whether you send manned or unmanned crafts or other deciding factors (maybe you spend some money to hype the project to get more grants or even scientists to join your team. The more you explore the more you see. Send you a "Hubble" and you see more of your solar system/universe. Well I think you all get the idea. I bet this all has been already thought of, but hopefully there might be a nugget in there that can help. Thanks, Chad