I'm having this same problem on version 2.1.10.22
I can change the setting to follow mouse click on the current scene and it works but anytime I go to a new scene or restart the game it reverts to follow mouse.
persistents https://file.io/o7Gh9IyaT1cP
Mods https://file.io/aN4Ms4T2THvB
I don't know why it won't save the click setting.