I mean if I manually click on an instrument and transmit data it will transmit it normally. If I click on the SA button to log an experiment it will sometimes refuse to send any data (there are no log entries in the top left at all, clicking on 'transmit' doesn't do anything). Reloading helps as well - for example if my probe doesn't want to send data I can do a quicksave and quickreload and it will work again. Last time it happened I did a science junior experiment and I clicked on transmit data and it made the experiment void (it removed data and made it inoperable) but it didn't send any data and I couldn't run the experiment again. Without RemoteTech I don't have this issue. Similarly with RemoteTech (and without ScienceAlert) I also don't have this issue. But with both RT and SA it happens occasionally. PS: Maybe clicking on experiment manually or SA button has nothing to do with it if as you say they are the same (it could be biased observation since I mostly use SA button to gather science anyway). But I have this issue with like every 1 out of 20 times I'm playing around with experiments on unmanned probes. I also have a bunch of other mods (DMagic science, Interstellar etc...) so I will try to remove all other mods and see if this still happens.