I have a similar mod setup, as well as a set of graphics enhancement mods. CPU should be no problem, I'm running a Ryzen 3600X at about 20-50% load. RAM might be a bit tight, I have 32 gigs and I'm using anywhere from 16 to 20 consistently. My GPU is a 1660ti, and the 6GB of dedicated RAM is consistently maxed out. That appears to be the bottleneck, but it runs fairly well. I only really have major lag during loading screens, and occasionally when switching in and out of different scenes/map view.
Hope this helps!