RoninFrog

When you drop your SRB's, you lose your fins.  All the science gear on top is very non-aerodynamic, so it will create a lot of drag and your rocket will want to turn around.  You could either add fins to the base of the liquid fuel stage, or stick all the science stuff in a storage bay.

It should work.  It might not work if the fuel has to pass through a reaction wheel, But I don't think there are any other parts that block the flow of fuel.  Just make sure to enable crossfeed on the docking ports.