If you are decent at docking, or just really want to try it, i would suggest you get that into orbit. Assuming you have fuel left, i would suggest not dropping any tanks on the way up, minus SRBs. Next, launch a repeat of the craft, and dock up and transfer fuel to fully fuel up your craft. If you have the NERVAs, use those as much as possible, transferring fuel from the outer tanks with the bigger and less efficient engines, to the NERVA tanks. If Not, then you might need to design a few stages, and launch them up seperately, dock and combine them, then fuel missions til full, and set on out. Combine with Kethane pack for max longitivity of mission. My personal fun recommendation is the second option. I love overly complicated missions that could be done easier. So does jeb. They tend to blow up faster.