First of all, I'm so excited to finally see KSP 2 footage and obviously it's a blast with Matt Lowne (the commentaries man ).
As a first impression, I feel like there is going to be some adjustments with the parts manager both in flight and the VAB, just some getting used to. Something however, that particularly bugged me (although I suppose this is a personal view) is the lack of brightness in the VAB especially when your color palette like Matt's dark blue is used. Maybe would it be possible to have a slider to increase the overall brightness around the rocket?
Next, up in space the apoapsis and periapsis information is below the nav ball. So when Matt's hovered over the periapsis after circularizing around Kerbin, the label that popped up was just "Kerbin". Maybe it would be nice to have more information for the different points in the orbit and maneuver nodes, just a thought.
Then, the big concentric circles for sphere of influence in/out are pretty huge imo.
Like Matt correctly pointed out the mun looks gorgeous up high, but up close not as much, maybe parallax will come in handy in KSP2.
And the crafts floating on water probably needs some tuning lol.
Anyways that's it, just some small things. Excited for the 24th