I am running into the same issue. I am running KSP with Realism Overhaul, Mechjeb, Kerbal Engineer, KWRocketry and FASA. All Mods are the latest version downloaded yesterday and manually installed on a clean installation of KSP. Pretty much my rocket breaks up on the Launchpad as soon as I load it from the VAB. I can only sometimes launch if I place 4 launch clamps on the first or second stage engines but its a 50/50 chance. If I quicksave and revert, the rocket always falls apart when I load the quicksave. Its a fairly large recreation of the Saturn V. The craft file can be downloaded at https://www.dropbox.com/s/v46mtenr5sroez6/Saturn%20V.craft?dl=0. I am at my wits ends trying to get this thing to launch and I think the issue relates to KJR since the breakup happens right after the KJR message shows. The rocket always separates at engines with both the 1st and 2nd Stage engines falling off. A picture of my GameData folder can be found at this link. https://www.dropbox.com/s/jdvoieyckftr06i/KSP.JPG?dl=0 [EDIT] Just out of curiosity, I downgraded from 3.0.1 to 2.4.5 and it eliminated the problem. Will keep using the old version of KJR until the bug gets fixed.