1. You don't need to add 6.000 boosters to make rocket fly. Just make things simple and it will easily take you to the moon
2. If you don't know how to dock you will never make any big space station, or go behind minimus with manned vessel.
3. You dont need to use nay autopilots to go to the orbit, you need to know what does every indicator on the navball do.
4. When building a plane make your center of lift a little behind center of mass.
5. Don't place your front landing gear in middle of you aircraft, because it makes your plane flipping on start.
6. Lift is more important than thrust when building your space plane - without enginesyou can glide for very long time, without wings you fall like a brick instantly.
EDIT: Sheesh, my English wasn't that great back when I wrote it...