Yes. I've just started a new career mode save and I'm finding it really fun. My favourite thing to do is set up a space station. It's really satisfying and I'm quite good at it. SSTOs/spaceplanes are fun too.
The main issue is the Hubble: it's in a polar orbit higher than the ISS, and even the shuttle didn't have enough fuel to get to the ISS from the HST, so there was no way that a MMU could do that.
eg. some people don't just dump their nuclear engines, they return them to Kerbin undamaged. There is no reason to do this yet, but RPers imagine the radiation.
Just started a new career mode save. Managed a rendezvous within my first 8 or so launches. Not quite as ambitious, but I had no trouble with it and so I feel proud of myself.