Spaceplanes are fun. -Use MechJeb or KER for Delta V readouts. If you want to LKO(70x70 orbit), you want 2.3km/s of Delta V with ONLY rockets. -Try RAPIER engines for your first one. They give quite the thrust at altitude. - For the first few flights, have small cargo, getting bigger until you can't make orbit. Flight: This is a universal rule. Pitch according to engine thrust. If you're seeing that (airbreathing) engine thrust is declining, pitch down. Pitch up so as long as you are still accelerating. At around 10km in altitude, make sure to stay level(ish). In this altitude of the ascent, you need to milk as much speed as possible from your engines. After thrust begins declining, wait until you're speed starts to lose acceleration. When that happens, activates rockets and continue ascent as if your a rocket that did an early gravity turn. Reentry: Don't go in nose-first. Do whatever to bleed speed before you get in the thicker air. Looking forward to see your designs!